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Pain Disorders

Plantar Fasciitis (PF)

Plantar fasciitis is a painful localized inflammatory condition which is frequently associated with debilitating pain in the heel and bottom of the foot, significantly impairing mobility.

Plantar Fasciitis might heal after several months with conservative treatments like ice, stretches, and common pain-relievers. Many cases require steroid injections, physical therapy, shock-wave therapy or surgery. Currently, there are no FDA-approved drug treatments for this debilitating yet common condition. An approved pharmacological treatment would potentially provide a significant step forward for this patient population. Plantar fasciitis is typically treated by podiatrists and orthopedic surgeons.

Enrollment for the Phase 2 placebo-controlled clinical trial of DaxibotulinumtoxinA for Injection for the management of plantar fasciitis was completed in December 2019 and topline results are expected in the second half of 2020.
DaxibotulinumtoxinA for Injection is an investigational agent that has not been approved by the FDA.

1M

Estimated number of patient visits per year attributed to PF. 1

1 in 10

Estimated number of U.S. adults who will suffer from PF in their lifetime.1

$250M

Estimated PF U.S. treatment market.2

References

  1. Rosenbaum AJ, et al. Plantar Heel Pain. Med Clin N Am 98. 2014: 339–352
  2. Medscape. Available at: http://emedicine.medscape.com/article/86143-overview. Accessed 27 August 2019.
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